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Rabbit anti-EPS8L2 Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
EPS8L2
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
between 600 and 650
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

100 µl (10 blots)

20 µl (2 blots)

For ordering information, see our International Distributors

Product Details

Specifications
Verified Reactivity
Human
Presumed Reactivity
Orangutan
Antigen Species
Human
Stock Concentration
100 µg/ml
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to EPS8L2 immobilized on solid support.

The epitope recognized by A301-841A-T maps to a region between residue 600 and 650 of human epidermal growth factor receptor pathway substrate 8-like protein 2 using the numbering given in entry NP_073609.2 (GeneID 64787).

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Gene & Protein Information

EPS8L2 (epidermal growth factor receptor kinase substrate 8-like protein 2) bears significant similarity to eps8. Like eps8, EPS8L2 has been shown to interact with SOS-1, a guanine nucleotide exchange factor (GEF), and activate its Rac-GEF activity. EPS8L2 localizes to PDGF-induced F-actin rich ruffles and plays a role in mediating receptor-tyrosine kinase activated actin remodeling.

64787

EPS8L2

EPS8 like 2

Q9H6S3

Epidermal growth factor receptor kinase substrate

Alternate Names

DFNB106, epidermal growth factor receptor kinase substrate 8-like protein 2, epidermal growth factor receptor pathway substrate 8-related protein 2, EPS8-like protein 2, EPS8R2, EPS8-related protein 2

Applications

Western blot of immunoprecipitates performed using Normal Pig Serum (Cat. No. S100-020), Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) and 4-8% SDS-PAGE. Western blot of lysates performed using standard western blot reagents and 4-8% SDS-PAGE.