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Rabbit anti-ERC1 Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
ERC1
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
between 1000 and 1050
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (200 µg/ml)

100 µl (10 blots)

20 µl (2 blots)

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Product Details

Specifications
Verified Reactivity
Human
Presumed Reactivity
Mouse
Antigen Species
Human
Stock Concentration
40 µg/ml
200 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to ERC1 immobilized on solid support.

The epitope recognized by A302-698A-T maps to a region between residue 1000 and 1050 of human ELKS/RAB6-interacting/CAST family member 1 using the numbering given in entry NP_829884.1 (GeneID 23085).

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Gene & Protein Information

ERC1 (ELKS/RAB6-interacting/CAST family member 1) is a regulatory subunit of the IkappaB kinase (IKK) complex. ERC1 probably recruits IkappaBalpha/NFKBIA to the IKK complex. ERC1 may be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release, and may also be involved in vesicle trafficking at the CAZ. ERC1 is also likely involved in Rab-6 regulated endosomes-to- Golgi transport [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8IUD2].

23085

ERC1

ELKS/RAB6-interacting/CAST family member 1

Q8IUD2

ELKS/Rab6-interacting/CAST family member 1

Alternate Names

Cast2, ELKS, ELKS/Rab6-interacting/CAST family member 1, ERC-1, RAB6 interacting protein 2, Rab6-interacting protein 2, RAB6IP2

Applications

Western blot of immunoprecipitates performed using Normal Pig Serum (Cat. No. S100-020), Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) and 4-8% SDS-PAGE. Western blot of lysates performed using standard western blot reagents and 4-8% SDS-PAGE.