Rabbit anti-ERC1 Antibody Affinity Purified
Product Details
Specifications
Additional Product Information
ERC1 (ELKS/RAB6-interacting/CAST family member 1) is a regulatory subunit of the IkappaB kinase (IKK) complex. ERC1 probably recruits IkappaBalpha/NFKBIA to the IKK complex. ERC1 may be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release, and may also be involved in vesicle trafficking at the CAZ. ERC1 is also likely involved in Rab-6 regulated endosomes-to- Golgi transport [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8IUD2].
Alternate Names
Cast2; ELKS; ELKS/Rab6-interacting/CAST family member 1; ERC-1; RAB6 interacting protein 2; Rab6-interacting protein 2; RAB6IP2
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.