/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-EVPL Antibody
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Primary Antibodies  

Rabbit anti-EVPL Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

EVPL

Reactivity:

Human

Applications:

IP

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 1983 and 2033

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

Envoplakin is a member of the plakin family of proteins that forms a component of desmosomes and the epidermal cornified envelope. The gene is located in the tylosis oesophageal cancer locus on chromosome 17q25, and its deletion is associated with both familial and sporadic forms of oesophageal squamous cell carcinoma. Patients suffering from the autoimmune mucocutaneous disorder, paraneoplastic pemphigus, develop antibodies against Envoplakin [taken from NCBI Entrez Gene (Gene ID: 2125)].

2125

EVPL

envoplakin

Q92817

Envoplakin

Alternate Names

210 kDa cornified envelope precursor protein; 210 kDa paraneoplastic pemphigus antigen; envoplakin; EVPK; p210

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.