Bethyl Laboratories
Rabbit anti-FALZ/BPTF IHC Antibody Affinity Purified
Primary
Catalog #IHC-00521
TargetFALZ/BPTF
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC
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Product Description
FALZ is the largest subunit of the nucleosome-remodeling factor (NURF) which catalyzes nucleosome sliding and facilitates chromatin remodeling and transcription. FALZ bears a C-terminal bromodomain and a plant homeodomain (PHD) finger. The PHD finger has been demonstrated to bind methyl-lysine and may function to couple histone trimethylation with chromatin remodeling.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 1475 and 1525
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetFALZ/BPTF
Antigen Species
Human
Gene ID2186
Gene Symbol
BPTF
Gene Name
bromodomain PHD finger transcription factor
Uniprot IDQ12830
Protein Name
Nucleosome-remodeling factor subunit BPTF
Alternate Names
bromodomain and PHD domain transcription factor • bromodomain and PHD finger-containing transcription factor • FAC1 • FAL • Zfetal Alz-50 clone 1 protein • fetal Alz-50 reactive clone 1 • fetal Alzheimer antigen • NEDDFL • nucleosome remodeling factor, large subunit • nucleosome-remodeling factor subunit BPTF • NURF301
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to FALZ/BPTF immobilized on solid support.
The epitope recognized by IHC-00521 maps to a region between residue 1350 and 1400 of human Fetal Alzheimer Antigen (Bromodomain and PHD Domain Transcription Factor) using the numbering given in entry NP_872579.2 (GeneID 2186).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with tris-EDTA pH9.0 buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00521Open
Product DatasheetPDF · IHC-00521 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00521 · Lot 1 (current lot)Open
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