Rabbit anti-Fibroblast Activation Protein alpha/FAP Recombinant Monoclonal Antibody [BLR150J]
Catalog #
Fibroblast Activation Protein alpha/FAP
Human
ICC
,IHC
,IP
,WB
Rabbit
Recombinant Monoclonal
BLR150J
Whole IgG
Residues 26-760 (ECD)
IgG
Unconjugated
Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide
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Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
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Recombinant antibody was purified from cell culture supernatant.
Immunogen was a recombinant protein representing the extracellular domain of human Prolyl Endopeptidase FAP (residues 26-760, NP_004451.2).
USA
Fibroblast Activation Protein alpha, or FAP, is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. FAP is involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. [taken from NCBI Entrez Gene (Gene ID: 2191)].
Alternate Names
170 kDa melanoma membrane-bound gelatinase; dipeptidyl peptidase FAP; DPPIV; FAPA; FAPalpha; Fibroblast activation protein alpha; gelatine degradation protease FAP; integral membrane serine protease; post-proline cleaving enzyme; prolyl endopeptidase FAP; seprase; Serine integral membrane protease; SIMP; surface-expressed protease
Applications