Bethyl Laboratories
Rabbit anti-Filamin B IHC Antibody Affinity Purified
Primary
Catalog #IHC-00355
TargetFilamin B
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC
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Product Description
Filamin B is a cytoplasmic protein that functions to link cell membrane proteins to the actin cytoskeleton. Defects in Filamin B are associated with a number of diseases characterized by skeletal dysplasias and abnormalities.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 2552 and C-terminus
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
100 µg/ml
Target Identity
TargetFilamin B
Antigen Species
Human
Gene ID2317
Gene Symbol
FLNB
Gene Name
filamin B
Uniprot IDO75369
Protein Name
Filamin-B
Alternate Names
ABP-278 • ABP-280 • ABP-280 homolog • actin binding protein 278 • actin-binding-like protein • AOI • beta-filamin • FH1 • filamin B, beta • filamin homolog 1 • filamin-3 • filamin-B • FLN1L • FLN-B • Larsen syndrome 1 (autosomal dominant) • LRS1 • SCT • TABP • TAP • thyroid autoantigen • Truncated ABP • Truncated actin-binding protein
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to Filamin B immobilized on solid support.
The epitope recognized by IHC-00355 maps to a region between residue 2552 and 2602 of human filamin B, beta (actin binding protein 278) using the numbering given in entry NP_001448.2 (GeneID 2317).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00355Open
Product DatasheetPDF · IHC-00355 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00355 · Lot 1 (current lot)Open
Citations / Publications
Services
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