Rabbit anti-FLG2 Antibody Affinity Purified
Catalog #
FLG2
Human
WB
Rabbit
Polyclonal
Whole IgG
between 100 and 150
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
The FLG2 protein is upregulated by calcium, proteolyzed by calpain 1, and is involved in epithelial homeostasis. FLG2 is also required for proper cornification in skin, with defects in this gene being associated with skin diseases. This protein also has a function in skin barrier protection. In fact, in addition to providing a physical barrier, C-terminal fragments of this protein display antimicrobial activity against P. aeruginosa. [provided by RefSeq, Dec 2015] [taken from NCBI Entrez Gene (Gene ID: 388698)].
Alternate Names
filaggrin-2; FLG-2; ifapsoriasin; IFPS; intermediate filament-associated and psoriasis susceptibility protein; Intermediate filament-associated and psoriasis-susceptibility protein; PSS6
Applications