Rabbit anti-FOXM1 Antibody Affinity Purified
Catalog #
FOXM1
Human
IP
Rabbit
Polyclonal
Whole IgG
Between 450 and 500
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
USA
FOXM1 belongs to a large family of Forkhead transcription factors that possesses a winged-helix DNA-binding domain called Forkhead box (FOX). It is a transcription factor critical to cell cycle progression via its role in coordinating the G2/M phase transition. FOXM1 is ubiquitously expressed in proliferating cells but is absent in differentiated cells. FOXM1 overexpression has been detected in a variety of tumor types including breast, lung, prostate, and liver cancer, and appears to be involved in tumorigenesis-associated processes such as angiogenesis and metastasis. In light of these findings, FOXM1 has recently become an attractive target for anti-cancer therapy.
Alternate Names
a novel forkhead box M1 isoform FOXM1D; FKHL16; forkhead box protein M1; Forkhead, drosophila, homolog-like 16; forkhead-related protein FKHL16; FOXM1A; FOXM1B; FOXM1C; hepatocyte nuclear factor 3 forkhead homolog 11; HFH11; HFH-11; HNF-3; HNF-3/fork-head homolog 11; INS-1; M-phase phosphoprotein 2; MPHOSPH2; MPM-2 reactive phosphoprotein 2; MPP2; MPP-2; PIG29; transcription factor Trident; TRIDENT; winged-helix factor from INS-1 cells
Applications