/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-FOXP3 Recombinant Monoclonal Antibody [BLR034F]
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Primary Antibodies  

Rabbit anti-FOXP3 Recombinant Monoclonal Antibody [BLR034F]

bethyl
Bethyl Laboratories

Catalog #

Validated
Citations (2)
Target:

FOXP3

Reactivity:

Human

Applications:

ICC

,

IHC

,

IHC-IF

,

IP

,

mIF

,

WB

Platforms:

COMET™

,

PhenoImager™ HT

Host:

Rabbit

Clonality:

Recombinant Monoclonal

Clone:

BLR034F

Format:

Whole IgG

Immunogen:

Between 275 and 325

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Purified

100 µl (50+ tests)

10 µl (5+ tests)

$127.00 $482.00
Qty:
Bulk Request

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free


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Production Procedures

Recombinant antibody was purified from cell culture supernatant.

Immunogen was a peptide representing a region between residue 275 and 325 of human Forkhead box P3 using the numbering given in entry NP_054728.2 (Gene ID 50943).

Country of Origin

USA

Additional Product Information

FOXP3 is a transcriptional regulator which is crucial for the development and inhibitory function of regulatory T-cells (Treg). It plays an essential role in maintaining homeostasis of the immune system by allowing the acquisition of full suppressive function and stability of the Treg lineage, and by directly modulating the expansion and function of conventional T-cells. FOXP3 can act either as a transcriptional repressor or a transcriptional activator depending on its interactions with other transcription factors, histone acetylases and deacetylases.  [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BZS1].

50943

FOXP3

forkhead box P3

Q9BZS1

Forkhead box protein P3

Alternate Names

AIID; DIETER; forkhead box protein P3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; PIDX; scurfin; XPID

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.