Rabbit anti-FOXP3 Recombinant Monoclonal Antibody [BLR281L]
Catalog #
FOXP3
Human
ICC
,IHC
,IP
,WB
COMET™
Rabbit
Recombinant Monoclonal
BLR281L
Whole IgG
Between 275 and 325
IgG
Unconjugated
Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Recombinant antibody was purified from cell culture supernatant.
Immunogen was a peptide representing a region between residue 275 and 325 of human Forkhead box protein P3 using the numbering given in entry NP_054728.2 (Gene ID 50943).
USA
FOXP3 is a transcriptional regulator which is crucial for the development and inhibitory function of regulatory T-cells (Treg). It plays an essential role in maintaining homeostasis of the immune system by allowing the acquisition of full suppressive function and stability of the Treg lineage, and by directly modulating the expansion and function of conventional T-cells. FOXP3 can act either as a transcriptional repressor or a transcriptional activator depending on its interactions with other transcription factors, histone acetylases and deacetylases. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BZS1].
Alternate Names
AIID; DIETER; forkhead box protein P3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; PIDX; scurfin; XPID
Applications