Bethyl Laboratories
Rabbit anti-Gemin4 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00481
TargetGemin4
HostRabbit
ClonalityPolyclonal
ReactivityMouse, Human
ApplicationIHC
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Product Description
Gemin4 is a component of the SMN (survival of motor neurons) complex and also localizes to nuclear focal structures called gems or Gemini of coiled bodies. In the SMN complex Gemin4 interacts with the gemin3 DEAD box protein and several core components of the splicesome that mediates pre-mRNA splicing.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 1008 and C-terminus
Isotype
IgG
Reactivity
Mouse, Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetGemin4
Antigen Species
Human
Gene ID50628
Gene Symbol
GEMIN4
Gene Name
gem nuclear organelle associated protein 4
Uniprot IDP57678
Protein Name
Gem-associated protein 4
Alternate Names
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to Gemin4 immobilized on solid support.
The epitope recognized by IHC-00481 maps to a region between residue 1010 and the C-terminus (residue 1058) fo human Gem (nuclear organelle) Associated Protein 4 using the numbering given in entry NP_056536.1 (GeneID 50628).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with tris-EDTA pH9.0 buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00481Open
Product DatasheetPDF · IHC-00481 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00481 · Lot 1 (current lot)Open
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