Rabbit anti-GIT2 IHC Antibody
Catalog #
GIT2
Human
IHC
Rabbit
Polyclonal
Whole IgG
Between 500 and 550
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Guinea_pig,
Mouse,
Horse,
Zebra_finch,
Turkey,
Dog,
Chicken,
Pig,
Rabbit,
X_laevis,
X_tropicalis,
Bovine,
Monkey,
Rat
Human
2 - 8 °C
1 year from date of receipt
G-protein-coupled receptor kinase interactor 1 (GIT1) and G-protein-coupled receptor kinase interactor 2 (GIT2) are GTPase-activating proteins for ADP-ribosylation (Arf) GTPases. GIT1 and GIT2 regulate Arf activity and the sequestration of activated G protein-coupled receptors from the surface of the cell. These activities have effects on multiple cellular processes such as cell migration, T-cell activation, and centrosome dynamics. Both GIT proteins also serve as scaffolds to link signaling molecules.
Alternate Names
ARF GAP GIT2; ARF GTPase-activating protein GIT2; CAT2; CAT-2; cool-associated, tyrosine phosphorylated protein 2; cool-interacting tyrosine-phosphorylated protein 2; G protein-coupled receptor kinase interacting ArfGAP 2; G protein-coupled receptor kinase-interactor 2; GRK-interacting protein 2; Paxillin kinase linker; PKL
Applications