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Rabbit anti-GTF2I/TFII-I IHC Antibody Affinity Purified
Bethyl Laboratories
Catalog #
Validated
Target:
GTF2I/TFII-I
Reactivity:
Human
,Mouse
Applications:
IHC
,IHC-IF
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 948 and C-terminus
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
Product Details
Specifications
Verified Reactivity
Mouse,
Human
Human
Presumed Reactivity
Guinea Pig,
Horse,
Dog,
Pig,
Bovine,
Monkey,
Rat
Horse,
Dog,
Pig,
Bovine,
Monkey,
Rat
Dog,
Pig,
Bovine,
Monkey,
Rat
Pig,
Bovine,
Monkey,
Rat
Bovine,
Monkey,
Rat
Monkey,
Rat
Rat
Antigen Species
Human
Concentration
100 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Production Procedures
Antibody was affinity purified using an epitope specific to GTF2I/TFII-I immobilized on solid support.
The epitope recognized by IHC-00273 maps to a region between residue 985 and 998 of human general transcription factor II-I using the numbering given in entry NP_127492.1 (GeneID 2969).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Antibody was affinity purified using an epitope specific to GTF2I/TFII-I immobilized on solid support.
The epitope recognized by IHC-00273-T maps to a region between residue 985 and 998 of human general transcription factor II-I using the numbering given in entry NP_127492.1 (GeneID 2969).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Country of Origin
USA
Additional Product Information
GTF2I/TFII-I is a multi-functional transcription factor that interacts with the basal transcription machinery and links upstream cellular signals to responsive activator complexes that associate with the C-FOS promoter and other response elements. Haploinsufficiency of GTF2I/TFII-I results in Williams-Beuren syndrome (WBS), a rare developmental disorder characterized by musculo-skeletal and cardiac abnormalities.
Alternate Names
BAP135; BAP-135; Bruton tyrosine kinase-associated protein 135; BTKAP1; BTK-associated protein 135; BTK-associated protein, 135kD; DIWS; general transcription factor II-I; GTFII-I; IB291; SPIN; SRF-Phox1-interacting protein; TFII-I; WBS; WBSCR6; Williams-Beuren syndrome chromosomal region 6 protein; Williams-Beuren syndrome chromosome region 6
Applications