Bethyl Laboratories
Rabbit anti-GTSE1 Antibody Affinity Purified
Primary
Catalog #A302-425A
TargetGTSE1
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationWB
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Product Description
GTSE1 (G-2 and S-phase expressed 1) is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, GTSE1 accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis [taken from NCBI Entrez Gene (GeneID: 51512)].
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 689 and C-terminus
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
200 µg/ml
Target Identity
TargetGTSE1
Antigen Species
Human
Gene ID51512
Gene Symbol
GTSE1
Gene Name
G2 and S-phase expressed 1
Uniprot IDQ9NYZ3
Protein Name
G2 and S phase-expressed protein 1
Alternate Names
Product Information
Applications
WB
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to GTSE1 immobilized on solid support.
The epitope recognized by A302-425A maps to a region between residue 670 and 720 of human G-2 and S-phase expressed 1 using the numbering given in entry NP_057510.2 (GeneID 51512).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (A120-101P).
Western Blot (WB)1:2000 - 1:10,000
Documents
Product DatasheetPDF · A302-425A · Lot 1 (current lot)Open
Product DatasheetPDF · A302-425A · Lot 1 (current lot)Open
Safety Data SheetPDF · A302-425AOpen
Citations / Publications
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