Bethyl Laboratories
Rabbit anti-HDAC3 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00428
TargetHDAC3
HostRabbit
ClonalityPolyclonal
ReactivityMouse, Human
ApplicationIHC
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Product Description
Histone deacetylase 3 (HDAC3) is a class I histone deacetylase that catalyzes the removal of the acetyl group on lysine residues of the N-terminus of the core histones H2A, H2B, H3, and H4. HDAC3 is found in multi-protein complexes and its activity depends on its interaction with the co-repressors SMRT and N-CoR.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 378 and C-terminus
Isotype
IgG
Reactivity
Mouse, Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetHDAC3
Antigen Species
Human
Gene ID8841
Gene Symbol
HDAC3
Gene Name
histone deacetylase 3
Uniprot IDO15379
Protein Name
Histone deacetylase 3
Alternate Names
HD3 • histone deacetylase 3 • RPD3 • RPD3-2 • SMAP45
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to HDAC3 immobilized on solid support.
The epitope recognized by IHC-00428 maps to a region between residue 375 and the C-terminus (residue 428) of human Histone Deacetylase 3 using the numbering given in Swiss-Prot entry O15379 (GeneID 8841).
Applications
Epitope exposure is recommended.
Epitope exposure with tris-EDTA pH9.0 buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00428Open
Product DatasheetPDF · IHC-00428 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00428 · Lot 1 (current lot)Open
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