Bethyl Laboratories
Rabbit anti-HIF1-alpha Recombinant Monoclonal Antibody [BLGR048]New
Primary
Catalog #A701-048
TargetHIF1-alpha
HostRabbit
CloneBLGR048
ReactivityHuman
ApplicationIHC
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This item has an estimated lead time of two weeks.
Product Description
Hypoxia-inducible factor-1 (HIF1) is a basic helix-loop-helix (bHLH)-PER-ARNT-sim (PAS) transcription factor that plays a role in the cellular response to hypoxia. HIF1 is a heterodimer of an HIF1-alpha and HIF1-beta subunit. During normoxia, HIF-1alpha is regulated by ubiquitination and interaction with the von-Hippel-Lindau tumor suppressor protein (pVHL).
Specifications
Clonality
Recombinant Monoclonal
Clone
BLGR048
Host
Rabbit
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Purified
Target Identity
TargetHIF1-alpha
Antigen Species
Human
Gene ID3091
Gene Symbol
HIF1A
Gene Name
hypoxia inducible factor 1 alpha subunit
Uniprot IDQ16665
Protein Name
Hypoxia-inducible factor 1-alpha
Alternate Names
ARNT-interacting protein • basic-helix-loop-helix-PAS protein MOP1 • bHLHe78 • class E basic helix-loop-helix protein 78 • HIF1 • HIF-1A • HIF-1alpha • HIF-1-alpha • HIF1-ALPHA • hypoxia inducible factor 1 alpha subunit • hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) • hypoxia-inducible factor 1 alpha isoform I.3 • hypoxia-inducible factor 1-alpha • hypoxia-inducible factor1alpha • member of PAS protein 1 • member of PAS superfamily 1 • MOP1 • PAS domain-containing protein 8 • PASD8
Product Information
Applications
IHC
Buffer
Tris-buffered Saline with 1% BSA and <0.1% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Applications
Immunohistochemistry (IHC)1:50 to 1:200
Documents
Product DatasheetPDF · A701-048 · Lot 1 (current lot)Open
Product DatasheetPDF · A701-048 · Lot 1 (current lot)Open
Safety Data SheetPDF · A701-048Open
Services
Antibody Conjugation
Antibody and conjugate formats developed together, built to your specification.
Request CustomizationCustom Monoclonal Antibody Discovery Services
Full custom monoclonal development, from immunization through validation.
Explore Monoclonal DevelopmentVHH Discovery
Single-domain antibodies for structurally difficult targets a conventional monoclonal can't reach.
Explore VHH DiscoveryResources
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