Bethyl Laboratories
Rabbit anti-hSET1B IHC Antibody Affinity Purified
Primary
Catalog #IHC-00641
TargethSET1B
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC
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Product Description
hSET1B is a histone methyltransferase that associates in a complex with the non-catalytic subunits CFP1, Rbbp5, Ash2, Wdr5, and Wdr82. These five non-catalytic subunits are also part of the Set1A complex. The SET1B complex has been shown to catalyze the tri-methylation of ‘Lys-4’ on histone H3. SET1B has been shown to localize to sites independent of SET1A complexes indicating non-redundant functions between SET1B and SET1A complexes.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 350 and 400
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargethSET1B
Antigen Species
Human
Gene ID23067
Gene Symbol
SETD1B
Gene Name
SET domain containing 1B
Uniprot IDQ9UPS6
Protein Name
Histone-lysine N-methyltransferase SETD1B
Alternate Names
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to hSET1B immobilized on solid support.
The epitope recognized by IHC-00641 maps to a region between residue 350 and 400 of human SET domain containing 1B using the numbering given in entry NP_055863.1 (GeneID 23067).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00641Open
Product DatasheetPDF · IHC-00641 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00641 · Lot 1 (current lot)Open
Services
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