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Rabbit anti-ICOS Recombinant Monoclonal Antibody [BLR194J]

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

ICOS

Reactivity:

Human

Platforms:

COMET™

Host:

Rabbit

Clonality:

Recombinant Monoclonal

Clone:

BLR194J

Format:

Whole IgG

Immunogen:

between 149 and 199 (C-term)

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Purified

100 µl (50+ tests)

10 µl (5+ tests)

100 µg (BSA-Free)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
100 µg/ml 1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide


Request Formulation Change

Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free


Request Formulation Change

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Additional Product Information

ICOS is a member of the CD28 and CTLA-4 cell-surface receptor family. It enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. ICOS is essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y6W8].

29851

ICOS

inducible T cell costimulator

Q9Y6W8

Inducible T-cell costimulator

Alternate Names

activation-inducible lymphocyte immunomediatory molecule; AILIM; CD antigen CD278; CD278; CVID1; inducible costimulator; inducible T-cell costimulator; inducible T-cell co-stimulator

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.