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Rabbit anti-ICOS Recombinant Monoclonal Antibody [BLR194J]

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
ICOS
Reactivity:
Human
Host:
Rabbit
Clonality:
Recombinant Monoclonal
Clone:
BLR194J
Format:
Whole IgG
Immunogen:
between 149 and 199 (C-term)
IsoType:
IgG
Purity:
Purified
100 µl (50+ tests)

10 µl (5+ tests)

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Product Details

Specifications
Verified Reactivity
Human
Antigen Species
Human
Stock Concentration
100 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide
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Prod Procedures
Recombinant antibody was purified from cell culture supernatant.

Immunogen was a peptide representing a region between residue 149 and the C-terminus (residue 199) of human Inducible T-cell costimulator precursor (ICOS) using the numbering given in entry NP_036224.1 (Gene ID 29851).

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Gene & Protein Information

ICOS is a member of the CD28 and CTLA-4 cell-surface receptor family. It enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. ICOS is essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y6W8].

29851

ICOS

inducible T cell costimulator

Q9Y6W8

Inducible T-cell costimulator

Alternate Names

activation-inducible lymphocyte immunomediatory molecule, AILIM, CD antigen CD278, CD278, CVID1, inducible costimulator, inducible T-cell costimulator, inducible T-cell co-stimulator