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Rabbit anti-IL-10 Recombinant Monoclonal Antibody [BLR317M]
Bethyl Laboratories®
Catalog #
Validated
Target:
IL-10
Reactivity:
Human
Applications:
IHC
,IP
,WB
Host:
Rabbit
Clonality:
Recombinant Monoclonal
Clone:
BLR317M
Format:
Whole IgG
Immunogen:
residues 19-178
Isotype:
IgG
Purity:
Purified
100 µl (50+ tests)
10 µl (5+ tests)
Product Details
Specifications
Verified Reactivity
Human
Antigen Species
Human
Concentration
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Additional Product Information
IL-10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. IL-10 has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. [taken from NCBI Entrez Gene (Gene ID: 3586)].
Alternate Names
