Rabbit anti-IL-12B Recombinant Monoclonal Antibody [BLR322M]
Product Details
Specifications
Immunogen was a recombinant protein representing human IL-12B (residues 23-328, NP_002178.2).
Additional Product Information
IL-12B is a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD IL-12B, and the 35 kD subunit IL-12A. IL-12 is expressed by activated macrophages that serve as an essential inducer of Th1 cells development, and has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. [provided by RefSeq, Jul 2008; taken from NCBI Entrez Gene (Gene ID: 3593)].
Alternate Names
CLMF;CLMF p40;CLMF2;cytotoxic lymphocyte maturation factor 40 kDa subunit;IL-12 subunit p40;IL12, subunit p40;IL-12B;IMD28;IMD29;interleukin 12, p40;interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40);interleukin-12 beta chain;interleukin-12 subunit beta;natural killer cell stimulatory factor, 40 kD subunit;NK cell stimulatory factor chain 2;NKSF;NKSF2
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (A120-113P) with 5% Normal Pig Serum (S100-020) added to the blocking buffer.