Bethyl Laboratories
Rabbit anti-INCENP IHC Antibody Affinity Purified
Primary
Catalog #IHC-00060
TargetINCENP
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationICC-IF
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Product Description
INCENP (inner centromere protein) is a component of the chromosomal passenger complex (CPC) which is a group of proteins that localizes to the centromere during specific stages of the cell cycle. The CPC is key regulator of mitosis that functions in spindle assembly, chromosome alignment, and segregation. INCENP contains a coiled-coil domain that interacts with microtubules and is required for the spindle-assembly checkpoint.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 350 and 400
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetINCENP
Antigen Species
Human
Gene ID3619
Gene Symbol
INCENP
Gene Name
inner centromere protein
Uniprot IDQ9NQS7
Protein Name
Inner centromere protein
Product Information
Applications
ICC-IF
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to INCENP immobilized on solid support.
The epitope recognized by IHC-00060 maps to a region between residue 325 and 400 of human Inner Centromere Protein using the numbering given in entry Q9NQS7 (GeneID 3619).
Applications
Formaldehyde-Fixed Cells 1:100 - 1:500:
Permeabilization with Triton-X 100 is recommended.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunocytochemistry-Immunofluoresence (ICC-IF)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00060Open
Product DatasheetPDF · IHC-00060 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00060 · Lot 1 (current lot)Open
Citations / Publications
Services
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