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Rabbit anti-Integrin Alpha 6 Antibody Affinity Purified

bethyl
Bethyl Laboratories Catalog #
Validated
Target:
Integrin Alpha 6
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 50 and 100
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

$131.00 $464.00
Qty:

Product Details

Specifications

Verified Reactivity
Human
Presumed Reactivity
Mouse
Antigen Species
Human
Concentration
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Production Procedures
Antibody was affinity purified using an epitope specific to Integrin Alpha 6 immobilized on solid support.

The epitope recognized by A303-681A-T maps to a region between residue 50 and 100 of human Integrin, Alpha 6 using the numbering given in entry EAX11175.1 (GeneID 3655).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Antibody was affinity purified using an epitope specific to Integrin Alpha 6 immobilized on solid support.

The epitope recognized by A303-681A maps to a region between residue 50 and 100 of human Integrin, Alpha 6 using the numbering given in entry EAX11175.1 (GeneID 3655).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Country of Origin
USA

Additional Product Information

Integrin alpha 6 forms heterodimers with integrin beta 1 or beta 4 and functions as a receptor for the extracellular matrix protein, laminin. Integrin alpha 6 is encoded by the ITGA6 gene. Defects in ITGA6 are a cause of epidermolysis bullosa letalis with pyloric atresia (EB-PA) [MIM:226730]; also known as junctional epidermolysis bullosa with pyloric atresia (PA-JEB) or aplasia cutis congenita with gastrointestinal atresia. EB-PA is an autosomal recessive, frequently lethal, epidermolysis bullosa with variable involvement of skin, nails, mucosa, and with variable effects on the digestive system [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P23229].

3655
ITGA6
integrin subunit alpha 6
P23229
Integrin alpha-6

Alternate Names

CD antigen CD49f; CD49 antigen-like family member F; CD49f; integrin alpha-6; integrin alpha6B; integrin, alpha 6; ITGA6B; VLA-6

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.