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Rabbit anti-IP3R3 Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

IP3R3

Reactivity:

Human

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 650 and 700

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

$121.00 $433.00
Qty:

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Production Procedures

Antibody was affinity purified using an epitope specific to IP3R3 immobilized on solid support.

The epitope recognized by A302-159A-T maps to a region between residue 625 and 675 of human inositol 1, 4,5-triphosphate receptor, type 3 using the numbering given in entry NP_002215.2 (GeneID 3710).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.

Antibody was affinity purified using an epitope specific to IP3R3 immobilized on solid support.

The epitope recognized by A302-159A maps to a region between residue 625 and 675 of human inositol 1, 4,5-triphosphate receptor, type 3 using the numbering given in entry NP_002215.2 (GeneID 3710).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.

Country of Origin

USA

Additional Product Information

IP3R3 (inositol 1,4,5-triphosphate receptor type 3) is an intracellular calcium release channel that mediates calcium release from the endoplasmic reticulum. There are 3 mammalian IP3R receptors: IP3R1, IP3R2, and IP3R3. IP3R3 has been shown to play a role in olfactory mucus secretion and in the taste perception of sweet, savory (umami), and bitter substances.

3710

ITPR3

inositol 1,4,5-trisphosphate receptor type 3

Q14573

Inositol 1,4,5-trisphosphate receptor type 3

Alternate Names

inositol 1,4,5-triphosphate receptor, type 3; inositol 1,4,5-trisphosphate receptor type 3; insP3R3; IP3 receptor; IP3 receptor isoform 3; IP3R; IP3R 3; IP3R3; Type 3 inositol 1,4,5-trisphosphate receptor; type 3 InsP3 receptor

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (A120-113P) with 5% Normal Pig Serum (S100-020) added to the blocking buffer.