Bethyl Laboratories
Rabbit anti-IP3R3 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00639
TargetIP3R3
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC, IHC-IF
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Product Description
IP3R3 (inositol 1,4,5-triphosphate receptor type 3) is an intracellular calcium release channel that mediates calcium release from the endoplasmic reticulum. There are 3 mammalian IP3R receptors: IP3R1, IP3R2, and IP3R3. IP3R3 has been shown to play a role in olfactory mucus secretion and in the taste perception of sweet, savory (umami), and bitter substances.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 650 and 700
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetIP3R3
Antigen Species
Human
Gene ID3710
Gene Symbol
ITPR3
Gene Name
inositol 1,4,5-trisphosphate receptor type 3
Uniprot IDQ14573
Protein Name
Inositol 1,4,5-trisphosphate receptor type 3
Product Information
Applications
IHC, IHC-IF
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to IP3R3 immobilized on solid support.
The epitope recognized by IHC-00639 maps to a region between residue 625 and 675 of human inositol 1, 4,5-triphosphate receptor, type 3 using the numbering given in entry NP_002215.2 (GeneID 3710).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Immunohistochemistry-Immunofluoresence (IHC-IF)1:50 - 1:500
Documents
Safety Data SheetPDF · IHC-00639Open
Product DatasheetPDF · IHC-00639 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00639 · Lot 1 (current lot)Open
Citations / Publications
Services
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