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Primary Antibodies  

Rabbit anti-IQCB1 Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

IQCB1

Reactivity:

Human

Applications:

IP

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 548 and 598

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Presumed Reactivity

Mouse

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

IQ calmodulin-binding motif-containing protein 1 (IQCB1) is a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. IQCB1 has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. IQCB1 is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5 [taken from NCBI Entrez Gene (Gene ID: 9657)].

9657

IQCB1

IQ motif containing B1

Q15051

IQ calmodulin-binding motif-containing protein 1

Alternate Names

IQ calmodulin-binding motif-containing protein 1; nephrocystin 5; Nephrocystin-5; NPHP5; p53 and DNA damage-regulated IQ motif protein; PIQ; SLSN5

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.