Rabbit anti-KCC4 Antibody Affinity Purified
Product Details
Specifications
Additional Product Information
K-Cl cotransporter 4 (KCC4) mediates electroneutral potassium-chloride cotransport when activated by cell swelling. KCC4 may mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. KCC4 is important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. It may be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y666].
Alternate Names
electroneutral potassium-chloride cotransporter 4; KCC4; K-Cl cotransporter 4; potassium/chloride transporter KCC4; solute carrier family 12 (potassium/chloride transporter), member 7; solute carrier family 12 (potassium/chloride transporters), member 7; solute carrier family 12 member 7; SUCO/SLC12A7 fusion
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.