Bethyl Laboratories
Rabbit anti-KIFC1 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00496
TargetKIFC1
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC
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Product Description
The kinesin superfamily of proteins consists of over forty KIF motor proteins that function in intracellular transport along microtubules. Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, chromosome congression, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. KIFC1 has been demonstrated to be involved in the localization of PLK1, Aurora B, and Cdc14A to the central spindle during anaphase.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 623 and C-terminus
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetKIFC1
Antigen Species
Human
Gene ID3833
Gene Symbol
KIFC1
Gene Name
kinesin family member C1
Uniprot IDQ9BW19
Protein Name
Kinesin-like protein KIFC1
Alternate Names
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to KIFC1 immobilized on solid support.
The epitope recognized by IHC-00496 maps to a region between residue 625 and 673 of human Kinesin Family Member C1 using the numbering given in entry NP_002254.1 (GeneID 3833).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with tris-EDTA pH9.0 buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00496Open
Product DatasheetPDF · IHC-00496 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00496 · Lot 1 (current lot)Open
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