Bethyl Laboratories
Rabbit anti-LAP1B IHC Antibody Affinity Purified
Primary
Catalog #IHC-00537
TargetLAP1B
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC
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Product Description
Lamina-associated polypeptide 1B (LAPB1) binds to A- and B-type lamins. It is a single-pass membrane protein that localizes to the inner membrane of the nucleus and may play a role in membrane attachment and the assembly of the nuclear lamina. LAPB1 is also called torsin-1A-interacting protein 1 (TOR1AIP1) due to its association with torsin, an ATPase of the AAA- (adenosine triphosphatases associated with diverse cellular activities) family of proteins.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 275 and 325
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetLAP1B
Antigen Species
Human
Gene ID26092
Gene Symbol
TOR1AIP1
Gene Name
torsin 1A interacting protein 1
Uniprot IDQ5JTV8
Protein Name
Torsin-1A-interacting protein 1
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to LAP1B immobilized on solid support.
The epitope recognized by IHC-00537 maps to a region between residue 275 and 325 of human lamina associated polypeptide 1B using the numbering given in entry NP_056417.2 (GeneID 26092).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00537Open
Product DatasheetPDF · IHC-00537 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00537 · Lot 1 (current lot)Open
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