Bethyl Laboratories

Rabbit anti-LARP1 IHC Antibody Affinity Purified

Primary
Catalog #IHC-00559
TargetLARP1
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC
Detection of human LARP1 by immunohistochemistry.
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Product Description

LARP1 (la-related protein 1) is part of a family of proteins that bears a La motif. The La motif was first identified in the La protein which was isolated as an autoreactive antigen in patients afflicted with systemic lupus erythematosus. Like the La protein, LARP proteins appear to be RNA-binding proteins, and are proposed to play a role in translation elongation and termination.

Specifications

Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 575 and 625
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetLARP1
Antigen Species
Human
Gene ID23367
Gene Symbol
LARP1
Gene Name
La ribonucleoprotein domain family member 1
Uniprot IDQ6PKG0
Protein Name
La-related protein 1
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA

Production & Epitope

Antibody was affinity purified using an epitope specific to LARP1 immobilized on solid support.

The epitope recognized by IHC-00559 maps to a region between residue 575 and 625 of human La ribonucleoprotein domain family, member 1 using the numbering given in entry NP_291029.2 (GeneID 23367).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.

Applications

Epitope exposure is recommended.

Epitope exposure with citrate buffer will enhance staining.

Likely to work with frozen sections.

In some cases, the antibody may be diluted further than indicated.

Immunohistochemistry (IHC)1:100 - 1:500

Documents

Safety Data SheetPDF · IHC-00559Open
Product DatasheetPDF · IHC-00559 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00559 · Lot 1 (current lot)Open

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