Rabbit anti-LATS1 Antibody Affinity Purified
Catalog #
LATS1
Human
,Mouse
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 50 and 100
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Human
Human
2 - 8 °C
1 year from date of receipt
USA
LATS1 (Large Tumor Suppressor homolog 1) has been identified as a tumor suppressor protein linked to sarcomas and ovarian cancer. LATS1 is a member of the Dbf2-related (NDR) family of protein kinases that are key components of the mitotic exit network. LATS1 interacts with MOB1 and CDC2 kinase in early mitosis. LATS1 appears to negatively regulate G2/M transitioning by down-regulating CDC2 kinase activity.
Alternate Names
h-warts; large tumor suppressor homolog 1; LATS (large tumor suppressor, Drosophila) homolog 1; LATS, large tumor suppressor, homolog 1; serine/threonine-protein kinase LATS1; WARTS; WARTS protein kinase; wts
Applications