Bethyl Laboratories
Rabbit anti-Leo1 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00573
TargetLeo1
HostRabbit
ClonalityPolyclonal
ReactivityMouse, Human
ApplicationIHC
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Product Description
Leo1 is a component of the Paf/RNA polymerase II complex which consists of at least Leo1, CDC73, PAF1, and CTR9. The PAF1/RNA polymerase II complex plays a role in transcriptional initiation and elongation, histone methylation, and RNA processing.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 550 and 600
Isotype
IgG
Reactivity
Mouse, Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
100 µg/ml
Target Identity
TargetLeo1
Antigen Species
Human
Gene ID123169
Gene Symbol
LEO1
Gene Name
LEO1 homolog, Paf1/RNA polymerase II complex component
Uniprot IDQ8WVC0
Protein Name
RNA polymerase-associated protein LEO1
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to Leo1 immobilized on solid support.
The epitope recognized by IHC-00573 maps to a region between residues 550 and 600 of human senescence downregulated leo1-like using the numbering given in TrEMBL entry Q8WVC0 (GeneID 123169).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with tris-EDTA pH9.0 buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00573Open
Product DatasheetPDF · IHC-00573 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00573 · Lot 1 (current lot)Open
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