Bethyl Laboratories
Rabbit anti-LTBR/Lymphotoxin-beta Receptor Antibody Affinity Purified
Primary
Catalog #A305-189A
TargetLTBR/Lymphotoxin-beta Receptor
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIP, WB
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Product Description
Tumor necrosis factor receptor superfamily member 3, also known as lymphotoxin-beta receptor, is encoded for by the gene LTBR. A member of the tumor necrosis factor receptor superfamily, the major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death [taken from NCBI Entrez Gene (Gene ID: 4055)].
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 385 and C-terminus
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
1000 µg/ml
Target Identity
Antigen Species
Human
Gene ID4055
Gene Symbol
LTBR
Gene Name
lymphotoxin beta receptor
Uniprot IDP36941
Protein Name
Tumor necrosis factor receptor superfamily member 3
Alternate Names
D12S370 • LT-BETA-R • lymphotoxin B receptor • lymphotoxin beta receptor (TNFR superfamily, member 3) • Lymphotoxin-beta receptor • TNFCR • TNFR2-RP • TNFR3 • TNF-RIII • TNF-R-III • TNFR-III • TNFR-RP • TNFRSF3 • tumor necrosis factor C receptor • tumor necrosis factor receptor 2-related protein • tumor necrosis factor receptor superfamily member 3 • tumor necrosis factor receptor type III
Product Information
Applications
IP, WB
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to LTBR/Lymphotoxin-beta Receptor immobilized on solid support.
The epitope recognized by A305-189A maps to a region between residue 385 to 435 of human Tumor necrosis factor receptor superfamily member 3 using the numbering given in entry P36941.1 (GeneID 4055).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (A120-101P).
Western blots of immunoprecipitates are performed using an anti-Rabbit IgG Light Chain HRP-conjugated antibody with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.
Immunoprecipitation (IP)6 µg/mg lysate
Western Blot (WB)1:1000 - 1:5000
Documents
Product DatasheetPDF · A305-189A · Lot 1 (current lot)Open
Product DatasheetPDF · A305-189A · Lot 1 (current lot)Open
Safety Data SheetPDF · A305-189AOpen
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