Rabbit anti-LZTS2 Antibody Affinity Purified
Catalog #
LZTS2
Human
IP
Rabbit
Polyclonal
Whole IgG
Between 619 and C-terminus
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse,
Bovine,
Rat
Bovine,
Rat
Rat
Human
2 - 8 °C
1 year from date of receipt
USA
leucine zipper, putative tumor suppressor 2 (LZTS2) is az negative regulator of katanin-mediated microtubule severing and release from the centrosome. It is required for central spindle formation and the completion of cytokinesis. LZTS2 may negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. It is a negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BRK4].
Alternate Names
hLZTS2; LAPSER1; leucine zipper putative tumor suppressor 2; leucine zipper, putative tumor suppressor 2; protein LAPSER1
Applications