Bethyl Laboratories
Rabbit anti-MADD IHC Antibody Affinity Purified
Primary
Catalog #IHC-00621
TargetMADD
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC, IHC-IF
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Product Description
MAP kinase-activating death domain protein (MADD) is a death domain containing protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activate protein kinase (MAPK) and transduce apoptotic signals. MADD is a multi-pass membrane protein that exists as multiple alternatively spliced forms.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 1597 and C-terminus
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
100 µg/ml
Target Identity
TargetMADD
Antigen Species
Human
Gene ID8567
Gene Symbol
MADD
Gene Name
MAP kinase activating death domain
Uniprot IDQ8WXG6
Protein Name
MAP kinase-activating death domain protein
Product Information
Applications
IHC, IHC-IF
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to MADD immobilized on solid support.
The epitope recognized by IHC-00621 maps to a region between residue 1597 and 1647 of human MAP-kinase activating death domain using the numbering given in entry NP_003673.3 (GeneID 8567).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Immunohistochemistry-Immunofluoresence (IHC-IF)1:50 - 1:500
Documents
Safety Data SheetPDF · IHC-00621Open
Product DatasheetPDF · IHC-00621 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00621 · Lot 1 (current lot)Open
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