Bethyl Laboratories
Rabbit anti-MAML3 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00447
TargetMAML3
HostRabbit
ClonalityPolyclonal
ReactivityMouse, Human
ApplicationIHC
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Product Description
There are 3 MAML (mastermind-like) proteins in mammals (MAML1-3). MAML3 is a coactivator for NOTCH signaling. MAML3 associates with NOTCH and CSL in a ternary complex and functions to activate transcription of HES and hairy-related basic helix-loop-helix transcription factors.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 1088 and C-terminus
Isotype
IgG
Reactivity
Mouse, Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
100 µg/ml
Target Identity
TargetMAML3
Antigen Species
Human
Gene ID55534
Gene Symbol
MAML3
Gene Name
mastermind like transcriptional coactivator 3
Uniprot IDQ96JK9
Protein Name
Mastermind-like protein 3
Alternate Names
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to MAML3 immobilized on solid support.
The epitope recognized by IHC-00447 maps to a region between residue 1100 and the C-terminus (residue 1133) human Mastermind-Like 3 using the numbering given in entry NP_061187.2 (GeneID 55534).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with tris-EDTA pH9.0 buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00447Open
Product DatasheetPDF · IHC-00447 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00447 · Lot 1 (current lot)Open
Services
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