Rabbit anti-Matrin 3 IHC Antibody Affinity Purified

Product Details
Specifications
The epitope recognized by IHC-00081 maps to a region between residue 800 and the C-terminus (residue 847) of human Matrin 3 using the numbering given in entry NP_061322.2 (GeneID 9782). Antibody was affinity purified using an epitope specific to Matrin 3 immobilized on solid support.
The epitope recognized by IHC-00081-T maps to a region between residue 800 and the C-terminus (residue 847) of human Matrin 3 using the numbering given in entry NP_061322.2 (GeneID 9782).
Additional Product Information
Matrin 3 is a nuclear matrix protein that has been observed to mediate multiple cellular processes. Matrin 3 can function to withhold defective RNAs within the nucleus by anchoring them to the nuclear matrix and modulate the promoter activity of genes proximal to matrix/scaffold attachment region (MAR/SAR). Matrin 3 has also been demonstrated to be the main PKA substrate following NMDA receptor activation in NMDA-induced neuronal cell death.
Alternate Names
ALS21; matrin-3; MPD2; VCPDM; vocal cord and pharyngeal weakness with distal myopathY
Applications
Epitope exposure is recommended.