Bethyl Laboratories
Rabbit anti-MCM3 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00066
TargetMCM3
HostRabbit
ClonalityPolyclonal
ReactivityMouse, Human
ApplicationIHC
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Product Description
The MCM (Mini-Chromosome Maintenance) complex is a key component of the pre-replication complex involved in replication licensing which restricts DNA replication to only once per cell cycle. The MCM complex is a heterohexamer of MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7. MCM3 has been shown to interact with MCM5, CDC46, and the acetyltransferase MCM3AP.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 500 and 550
Isotype
IgG
Reactivity
Mouse, Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetMCM3
Antigen Species
Human
Gene ID4172
Gene Symbol
MCM3
Gene Name
minichromosome maintenance complex component 3
Uniprot IDP25205
Protein Name
DNA replication licensing factor MCM3
Alternate Names
cervical cancer proto-oncogene 5 • DNA polymerase alpha holoenzyme-associated protein P1 • DNA replication factor MCM3 • DNA replication licensing factor MCM3 • HCC5 • hRlf beta subunit • MCM3 minichromosome maintenance deficient 3 • minichromosome maintenance deficient 3 • P1.h • p102 • P1-MCM3 • replication licensing factor, beta subunit • RLF subunit beta • RLFB
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to MCM3 immobilized on solid support.
The epitope recognized by IHC-00066 maps to a region between residues 500 and 550 of human Minichromosome Maintenance 3 using the numbering given in entry NP_002379.2 (GeneID 4172).
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00066Open
Product DatasheetPDF · IHC-00066 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00066 · Lot 1 (current lot)Open
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