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Rabbit anti-MEK1 Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
MEK1
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
between 343 and 393
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

100 µl (10 blots)

20 µl (2 blots)

For ordering information, see our International Distributors

Product Details

Specifications
Verified Reactivity
Human
Presumed Reactivity
X. laevis Chimpanzee Rabbit
Antigen Species
Human
Stock Concentration
100 µg/ml
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to MEK1 immobilized on solid support.

The epitope recognized by A302-140A-T maps to a region between residue 343 and 393 of human MAPK/ERK kinase 1 (Dual specificity mitogen-activated protein kinase kinase 1) using the numbering given in entry NP_002746.1 (GeneID 5604).

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Gene & Protein Information

MEK1 is an activator and kinase for MAP and ERK kinases. It is a serine/threonine kinase essential to the MAP kinase signal transduction pathway which is involved in a multitude of cellular processes such as proliferation, differentiation, gene activation, and development. MEK1 displays 85% identity with MEK2. Although MEK1 and MEK2 have been found to be functionally similar, they may serve non-redundant functions. Both are required for cellular proliferation and may play a role in tumorigenesis.

5604

MAP2K1

mitogen-activated protein kinase kinase 1

Q02750

Dual specificity mitogen-activated protein kinase

Alternate Names

CFC3, dual specificity mitogen-activated protein kinase kinase 1, ERK activator kinase 1, MAP kinase kinase 1, MAPK/ERK kinase 1, MAPKK 1, MAPKK1, MEK 1, MEK1, MKK1, PRKMK1, protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1)

Applications

Western blot of lysates performed using standard western blot reagents and 4-20% SDS-PAGE.

Citations (1)