Bethyl Laboratories
Rabbit anti-MEK2 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00620
TargetMEK2
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC
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Product Description
MEK2 (MAP2K2) is a dual specificity protein kinase that belongs to the MAP kinase kinase family. MEK2 is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3, and is involved in a multitude of cellular processes such as proliferation, differentiation, gene activation, and development [taken from NCBI Entrez Gene (Gene ID: 5605)].
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 1 and 50
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetMEK2
Antigen Species
Human
Gene ID5605
Gene Symbol
MAP2K2
Gene Name
mitogen-activated protein kinase kinase 2
Uniprot IDP36507
Protein Name
Dual specificity mitogen-activated protein kinase kinase 2
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to MEK2 immobilized on solid support.
The epitope recognized by IHC-00620 maps to a region between residue 1 and 50 of human MAPK/ERK kinase 2 using the numbering given in entry NP_109587.1 (GeneID 5605).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00620Open
Product DatasheetPDF · IHC-00620 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00620 · Lot 1 (current lot)Open
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