Rabbit anti-MerTK/c-mer Antibody Affinity Purified
Catalog #
MerTK/c-mer
Human
WB
Rabbit
Polyclonal
Whole IgG
Between 225 and 275
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Monkey
Human
2 - 8 °C
1 year from date of receipt
USA
MerTK/c-mer is one of three members (Tyro3, Axl, and MerTK/c-mer) of the Tyro 3 subfamily of receptor tyrosine kinases (RTK). MerTK/c-mer was cloned from a human B-lymphoblastoid cDNA library. MerTK/c-mer Expression is absent in normal lymphocytes but is found to be ectopically expressed in lymphoblasts and in T-cell ALL cell lines. When activated MerTK/c-mer transmits antiapoptotic and transforming signals and may play a significant role in T-cell leukemogenesis.
Alternate Names
c-Eyk; c-mer; c-mer proto-oncogene tyrosine kinase; MER; MER receptor tyrosine kinase; proto-oncogene c-Mer; receptor tyrosine kinase MerTK; RP38; STK kinase; Tyro12; tyrosine-protein kinase Mer
Applications