Bethyl Laboratories
Rabbit anti-MOF/MYST1 Antibody Affinity Purified
Primary
Catalog #A300-993A
TargetMOF/MYST1
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIP
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Product Description
MOF is a member of the MYST family of histone acetyltransferases (HAT). MOF has been shown to be required for histone H4 lysine K16-specific acetylation. MOF interacts with ATM (ataxia-telangiectasia-mutated) and may participate in the activation of ATM in response to DNA damage.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 408 and C-terminus
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
1000 µg/ml
Target Identity
TargetMOF/MYST1
Antigen Species
Human
Gene ID84148
Gene Symbol
KAT8
Gene Name
lysine acetyltransferase 8
Uniprot IDQ9H7Z6
Protein Name
Histone acetyltransferase KAT8
Alternate Names
histone acetyltransferase KAT8 • histone acetyltransferase MYST1 • hMOF • K(lysine) acetyltransferase 8 • Lysine acetyltransferase 8 • MOF • MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1 • MYST histone acetyltransferase 1 • MYST1 • MYST-1 • ortholog of Drosophila males absent on the first (MOF) • probable histone acetyltransferase MYST1 • ZC2HC8
Product Information
Applications
IP
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to MOF/MYST1 immobilized on solid support.
The epitope recognized by A300-993A maps to a region between residue 417 and the C-terminus (residue 458) of human males absent on the first (MYST histone acetyltransferase 1) using the numbering given in entry BAB13924.1 (GeneID 84148).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of immunoprecipitates are performed using an anti-Rabbit IgG Light Chain HRP-conjugated antibody with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.
Immunoprecipitation (IP)6 µg/mg lysate
Documents
Product DatasheetPDF · A300-993A · Lot 1 (current lot)Open
Product DatasheetPDF · A300-993A · Lot 1 (current lot)Open
Safety Data SheetPDF · A300-993AOpen
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