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Rabbit anti-NCoR Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
NCoR
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
between 2000 and 2050
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (200 µg/ml)

100 µl (10 blots)

20 µl (2 blots)

For ordering information, see our International Distributors

Product Details

Specifications
Verified Reactivity
Human
Antigen Species
Human
Stock Concentration
100 µg/ml
200 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to NCoR immobilized on solid support.

The epitope recognized by A301-146A-T maps to a region between residue 2000 and 2050 of human nuclear receptor co-repressor 1 using the numbering given in entry NP_006302.2 (GeneID 9611).

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Gene & Protein Information

The nuclear Receptor corepressor protein (NCoR) mediates gene repression by interacting with nuclear receptors such as the thyroid hormone receptor, retinoic acid receptor, progesterone receptor, androgen receptor, estrogen receptor, and glucocorticoids receptor. NCoR mediates repression by associating with SIN3A/B and the histone deacetylases, HDAC1 and HDAC2, and promoting the formation of repressive chromatin structures.

9611

NCOR1

nuclear receptor corepressor 1

O75376

Nuclear receptor corepressor 1

Alternate Names

hN-CoR, N-CoR, N-CoR1, nuclear receptor corepressor 1, PPP1R109, protein phosphatase 1, regulatory subunit 109, thyroid hormone- and retinoic acid receptor-associated corepressor 1, TRAC1

Applications

Western blot of immunoprecipitates performed using Normal Pig Serum (Cat. No. S100-020), Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) and 4-8% SDS-PAGE. Western blot of lysates performed using standard western blot reagents and 4-8% SDS-PAGE.

Citations (3)