/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-Notch1 IHC Antibody
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Primary Antibodies  

Bethyl Laboratories® Rabbit anti-Notch1 IHC Antibody, Affinity Purified - 100 µl (50+ slides)

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

Notch1

Reactivity:

Human

Applications:

IHC

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 2505 and C-terminus

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (50+ slides)

10 µl (5+ slides)

$121.00 $459.00
Qty:
Bulk Request

Product Details

Specifications
Verified Reactivity

Human

Presumed Reactivity

Monkey

Antigen Species

Human

Concentration
250 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Country of Origin

USA

Additional Product Information

Notch1 is the human homolog of the D. melanogaster Notch gene first reported as the gene responsible for the presence of notches in the wingblades of a specific strain of flies. The Notch protein is a transmembrane receptor that mediates juxtacrine signals between adjacent cells. Mammalian Notch1 ligands include Delta-like and Jagged. Upon ligand binding, Notch1 undergoes two proteolytic cleavage events that result in the release of the intracellular Notch1 domain and its translocation to the nucleus where it can participate in gene transactivation. Notch 1 signals mediate cellular fate, differentiation, and development.

4851

NOTCH1

notch 1

P46531

Neurogenic locus notch homolog protein 1

Alternate Names

AOS5; AOVD1; hN1; neurogenic locus notch homolog protein 1; Notch 1; Notch homolog 1, translocation-associated; TAN1; translocation-associated notch protein TAN-1

Applications

Epitope exposure is recommended.

Epitope exposure with citrate buffer will enhance staining.

Likely to work with frozen sections.

In some cases, the antibody may be diluted further than indicated.