Bethyl Laboratories
Rabbit anti-NUMBL Antibody Affinity Purified
Primary
Catalog #A301-718A
TargetNUMBL
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIP
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Product Description
NUMBL [numb (drosophila) homolog-like] is functionally related to NUMB, a protein that plays an essential role in the determination of cell fate for sensory organ and neural development. Polyglutamine repeats in the NUMBL gene have been associated with schizophrenia in two unrelated populations.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 225 and 275
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
1000 µg/ml
Target Identity
TargetNUMBL
Antigen Species
Human
Gene ID9253
Gene Symbol
NUMBL
Gene Name
NUMB like, endocytic adaptor protein
Uniprot IDQ9Y6R0
Protein Name
Numb-like protein
Alternate Names
CAG3A • CTG3a • NBL • numb homolog-like • NUMBLIKE • numb-like protein • NUMBR • NUMB-R • numb-related protein • TNRC23
Product Information
Applications
IP
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to NUMBL immobilized on solid support.
The epitope recognized by A301-718A maps to a region between residue 200 and 250 of human numb (Drosophila) homolog-like using the numbering given in entry NP_004747.1 (GeneID 9253).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of immunoprecipitates are performed using an anti-Rabbit IgG Light Chain HRP-conjugated antibody with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.
Immunoprecipitation (IP)6 µg/mg lysate
Documents
Product DatasheetPDF · A301-718A · Lot 1 (current lot)Open
Product DatasheetPDF · A301-718A · Lot 1 (current lot)Open
Safety Data SheetPDF · A301-718AOpen
Services
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