Bethyl Laboratories
Rabbit anti-OBFC2A Antibody Affinity Purified
Primary
Catalog #A302-254A
TargetOBFC2A
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIP
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Product Description
OBFC2A is also known as hSSB2 or SSB2 and is a homolog of hSSB1 (OBFC2B). OBFC2A, as well as OBFC2B are single-stranded binding proteins that contain an oligonucleotide/oliosaccharide binding fold (OB-fold). OB-fold proteins associate with each other to form multi-OB-fold complexes that associate with DNA-processing complexes that participate in DNA damage repair and replication. OBFC2A has been shown to protect genomic stability, and it is hypothesized that its participation in the DNA damage response may involve RAD51 and the ATM signaling pathway.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 1 and 50
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
1000 µg/ml
Target Identity
TargetOBFC2A
Antigen Species
Human
Gene ID64859
Gene Symbol
NABP1
Gene Name
nucleic acid binding protein 1
Uniprot IDQ96AH0
Protein Name
SOSS complex subunit B2
Alternate Names
hSSB2 • Nucleic acid-binding protein 1 • OBFC2A • oligonucleotide/oligosaccharide-binding fold containing 2A • oligonucleotide/oligosaccharide-binding fold-containing protein 2A • sensor of single-strand DNA complex subunit B2 • sensor of ssDNA subunit B2 • single-stranded DNA-binding protein 2 • SOSS complex subunit B2 • SOSS-B2 • SSB2
Product Information
Applications
IP
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to OBFC2A immobilized on solid support.
The epitope recognized by A302-254A maps to a region between residue 1 to 50 of human oligonucleotide/oligosaccharide-binding fold containing 2A using the numbering given in entry NP_001026886.1 (GeneID 64859).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of immunoprecipitates are performed using an anti-Rabbit IgG Light Chain HRP-conjugated antibody with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.
Immunoprecipitation (IP)6 µg/mg lysate
Documents
Product DatasheetPDF · A302-254A · Lot 1 (current lot)Open
Product DatasheetPDF · A302-254A · Lot 1 (current lot)Open
Safety Data SheetPDF · A302-254AOpen
Services
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