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Primary Antibodies

Rabbit anti-PARP1 Antibody Affinity Purified

Name: Rabbit anti-PARP1 Antibody
Brand: Bethyl Laboratories
SKU: A301-375A
Price: 121 USD

Bethyl Laboratories

Catalog #

Citations (2)

Target:

PARP1

Reactivity:

Human

Applications:

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 1 and 50

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (200 µg/ml)

10 µl (200 µg/ml)

$121.00 $433.00

Qty:

Product Details

Specifications

Verified Reactivity

Human

Presumed Reactivity

Bovine

Antigen Species

Human

Concentration

200 µg/ml

Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State

Liquid

Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide

Request Formulation Change

Production Procedures

Antibody was affinity purified using an epitope specific to PARP1 immobilized on solid support.

The epitope recognized by A301-375A maps to a region between residue 1 and 50 of human poly (ADP-ribose) polymerase family, member 1 using the numbering given in entry NP_001609.1 (GeneID 142).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.

Antibody was affinity purified using an epitope specific to PARP1 immobilized on solid support.

The epitope recognized by A301-375A-T maps to a region between residue 1 and 50 of human poly (ADP-ribose) polymerase family, member 1 using the numbering given in entry NP_001609.1 (GeneID 142).

Country of Origin

USA

Additional Product Information

PARP1 (Poly-ADP-ribose polymerase 1) is a member of PARP family of enzymes that transfer the ADP-D-ribosyl group of NAD(+) to an acceptor carboxyl group on proteins. PARP1 catalyzes the poly-ADP-ribosylation of histone and non-histone proteins in response to DNA damage. The over-activation of PARP-1 in response to DNA damage has been shown to promote cell and tissue injury. This observation has initiated research into the therapeutic potential of PARP1 inhibitors in the treatment of cancer, cardiovascular disease, and brain injury.

Gene ID:

142

Gene Symbol:

PARP1

Gene Name:

poly(ADP-ribose) polymerase 1

Uniprot ID:

P09874

Protein Name:

Poly [ADP-ribose] polymerase 1

Alternate Names

ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); ADP-ribosyltransferase diphtheria toxin-like 1; ADP-ribosyltransferase NAD(+); ADPRT; ADPRT 1; ADPRT1; ARTD1; NAD(+) ADP-ribosyltransferase 1; pADPRT-1; PARP; PARP-1; poly (ADP-ribose) polymerase family, member 1; poly ADP-ribose polymerase 1; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase; polyADP-ribose synthase 1; PPOL

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Rabbit anti-PARP1 Antibody Affinity Purified

Catalog #

PARP1

Human

WB

Rabbit

Polyclonal

Whole IgG

Between 1 and 50

IgG

Unconjugated

Antigen Affinity Purified

Human

Bovine

Human

2 - 8 °C

1 year from date of receipt

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide

Antibody was affinity purified using an epitope specific to PARP1 immobilized on solid support. The epitope recognized by A301-375A-T maps to a region between residue 1 and 50 of human poly (ADP-ribose) polymerase family, member 1 using the numbering given in entry NP_001609.1 (GeneID 142).

USA

142

PARP1

poly(ADP-ribose) polymerase 1

P09874

Poly [ADP-ribose] polymerase 1

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Antibody was affinity purified using an epitope specific to PARP1 immobilized on solid support.

The epitope recognized by A301-375A-T maps to a region between residue 1 and 50 of human poly (ADP-ribose) polymerase family, member 1 using the numbering given in entry NP_001609.1 (GeneID 142).

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).