Rabbit anti-PARP10 IHC Antibody Affinity Purified
Catalog #
PARP10
Human
,Mouse
IHC
Rabbit
Polyclonal
Whole IgG
Between 300 and 350
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Human
Human
2 - 8 °C
1 year from date of receipt
USA
PARP10 is a member of the poly(ADP-ribose) polymerase (PARP) family involved in a variety of processes which includes DNA metabolism, the DNA damage response, transcription and the maintenance of genomic stability. Although each member of the PARP family exhibits poly(ADP-ribose) polymerase activity which catalyzes the attachment of ADP-ribose units from NAD+ to substrate proteins, the endogenous substrates of many of the family members, including PARP10, remain to be identified. Recent studies have shown that PARP10 is localized to the nucleoli and associates with RNA polymerase II. PARP10 is a substrate of and is activated by CDK2 and may serve an important function in cell proliferation.
Alternate Names
ADP-ribosyltransferase diphtheria toxin-like 10; ARTD10; PARP-10; poly ADP-ribose polymerase 10
Applications