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Rabbit anti-Pds5B IHC Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

Pds5B

Reactivity:

Human

,

Mouse

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 1225 and 1275

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (50+ slides)

10 µl (5+ slides)

$121.00 $459.00
Qty:

Product Details

Specifications
Verified Reactivity

Mouse,

Human

Antigen Species

Human

Concentration
250 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Production Procedures

Antibody was affinity purified using an epitope specific to Pds5B immobilized on solid support.

The epitope recognized by IHC-00381 maps to a region between residues 1200 and 1250 of human Precocious Dissociation of Sisters-5B using the numbering given in entry CAB69911.1 (GeneID 23047).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.

Antibody was affinity purified using an epitope specific to Pds5B immobilized on solid support.

The epitope recognized by IHC-00381-T maps to a region between residues 1200 and 1250 of human Precocious Dissociation of Sisters-5B using the numbering given in entry CAB69911.1 (GeneID 23047).

Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.

Country of Origin

USA

Additional Product Information

Pds5B is a cohesin interacting protein. Cohesin functions to hold sister chromatids together during meiosis and mitosis and ensures proper segregation of chromosomes. Pds5B may play a specific role in the stabilization and destabilization of cohesin-mediated cohesion. Pds5B expression has been demonstrated to be androgen-induced and mediate the androgen-induced proliferative arrest of human prostate cells.

23047

PDS5B

PDS5 cohesin associated factor B

Q9NTI5

Sister chromatid cohesion protein PDS5 homolog B

Alternate Names

androgen induced inhibitor of proliferation; androgen-induced proliferation inhibitor; androgen-induced prostate proliferative shutoff-associated protein AS3; androgen-induced shutoff 3; APRIN; AS3; CG008; sister chromatid cohesion protein PDS5 homolog B

Applications

Epitope exposure is recommended.

Epitope exposure with citrate buffer will enhance staining.

Likely to work with frozen sections.

In some cases, the antibody may be diluted further than indicated.