Bethyl Laboratories
Rabbit anti-Pds5B IHC Antibody Affinity Purified
Primary
Catalog #IHC-00381
TargetPds5B
HostRabbit
ClonalityPolyclonal
ReactivityMouse, Human
ApplicationIHC, IHC-IF
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Product Description
Pds5B is a cohesin interacting protein. Cohesin functions to hold sister chromatids together during meiosis and mitosis and ensures proper segregation of chromosomes. Pds5B may play a specific role in the stabilization and destabilization of cohesin-mediated cohesion. Pds5B expression has been demonstrated to be androgen-induced and mediate the androgen-induced proliferative arrest of human prostate cells.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 1225 and 1275
Isotype
IgG
Reactivity
Mouse, Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetPds5B
Antigen Species
Human
Gene ID23047
Gene Symbol
PDS5B
Gene Name
PDS5 cohesin associated factor B
Uniprot IDQ9NTI5
Protein Name
Sister chromatid cohesion protein PDS5 homolog B
Product Information
Applications
IHC, IHC-IF
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to Pds5B immobilized on solid support.
The epitope recognized by IHC-00381 maps to a region between residues 1200 and 1250 of human Precocious Dissociation of Sisters-5B using the numbering given in entry CAB69911.1 (GeneID 23047).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Immunohistochemistry-Immunofluoresence (IHC-IF)1:50 - 1:500
Documents
Safety Data SheetPDF · IHC-00381Open
Product DatasheetPDF · IHC-00381 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00381 · Lot 1 (current lot)Open
Citations / Publications
Services
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