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Primary Antibodies  

Rabbit anti-PDZ-RhoGEF Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Citations (1)
Target:

PDZ-RhoGEF

Reactivity:

Human

Applications:

IHC

,

IP

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 125 and 175

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

PDZ-RhoGEF. (PDZ domain-containing Rho guanine nucleotide exchange factor) catalyzes the exchange of GDP for GTP on the GTPase, Rho, to activate downstream signaling pathways. It contains a PDZ [post synaptic density protein (PSD95), Drosophila dis large tumor suppressor (DIgA), and zonula occludens-1 protein (zo-1)] domain which is an 80-90 amino acid structural domain found in signaling proteins in bacteria, yeast, plants, and animals. PDZ-RhoGEF has been shown to be important to cell migration and the regulation of adhesion movement and trailing edge retraction.

9826

ARHGEF11

Rho guanine nucleotide exchange factor 11

O15085

Rho guanine nucleotide exchange factor 11

Alternate Names

glutamate transporter EAAT4-associated protein 48; GTRAP48; PDZ-RHOGEF; Rho guanine exchange factor (GEF) 11; Rho guanine nucleotide exchange factor (GEF) 11; rho guanine nucleotide exchange factor 11; RhoA-specific guanine nucleotide exchange factor; RhoGEF glutamate transport modulator

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.